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KMID : 0380020220370010001
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Korean Journal of Biotechnology and Bioengineering
2022 Volume.37 No. 1 p.1 ~ p.10
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Microbial Production and Industrial Applications of Keratinase
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Kim Min-Sung
Park Jong-Beom
Kim Jong-Nam
Kim Soo-Rin
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Abstract
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Keratin, which is the hard and insoluble structural protein found in many parts of birds, reptiles, and tissues such as feathers, hair, horns, wool. Some keratinaceous materials such as feathers known as industrial wastes, hard to degrade naturally because of their complex structure. To date, several bacteria and fungi have been discovered that have keratinase activity, which breaks down keratin into amino acids. In addition, various studies are being conducted to increase the activity of this enzyme through of recombinant keratinase or to facilitate purification. This potential enzyme can be used not only for the degradation of keratinaceous industrial wastes but also for the leather and healthcare industries. In this review, keratin degradation mechanisms, keratinase production, and their industrial applications will be discussed.
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KEYWORD
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keratinase, microbial keratinase, feather degradation, keratinaceous substrate, alkaline protease
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